Proton-pump inhibitors (e.g., omeprazole, esomeprazole, and lansoprazole), used to treat Zollinger-Ellison syndrome and gastroesophageal reflux disease (GERD), markedly decrease stomach acid secretion required for the release of vitamin B 12 from food but not from supplements
Detoxification entails the process of eliminating detrimental elements such as heavy metals, mold, yeast, fungus, pesticides, preservatives, and various chemicals from your system
This storage helps ensure the availability of B12 for metabolic processes
Open questions include tissue-selective delivery, chronic dosing effects on one-carbon metabolism, and interactions with NAD precursor strategies [14,8,9]