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Bach Knudsen KE, Lrke HN, Hedemann MS et al (2018) Impact of diet-modulated butyrate production on intestinal barrier function and inflammation

Results The number of human genes associated with stem cell function was 57 genes in the range of increases of 50% UP and 46 genes in the range of decreases of 50% DOWN

This sequence is derived from a larger, naturally occurring protein identified in human gastric fluid, first isolated and characterized in the early 1990s by a research team at the University of Zagreb in Croatia, led by Professor Predrag Sikiric

While the body produces its own supply, several factors can deplete these stores