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Patients in the ALC group also had scores on the FACT trial outcome index subscale (FACT-TOI), an overall measure of function, that were on average 3.5 points lower (worse) than those among their placebo counterparts (P = .03)

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This can cause uncomfortable symptoms, including: pelvic and back pain, fever and chills, burning or pain during urination, frequent urination, blood or pus in the urine, foul-smelling or cloudy urine, and more