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The single-dose injections were separated by 69 weeks of washout

The 6mL recommendation produces a 100 mg/mL concentration, which makes dosing math straightforward on an insulin syringe

Given the drugs success in tumor penetration, the researchers investigated whether adding immune checkpoint inhibitors to treatment with the drug would be even more effective, taking the brakes off T cells in more than one way at the same time but there was no such improvement