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Furthermore, with large-scale drug use it is inevitable that PZQ-resistant parasites will evolve, and PZQ resistance has been induced in laboratory infections 12

Fatigue or Lightheadedness: A temporary feeling of fatigue or lightheadedness has been reported, especially during the initial days of use

For example, glutathione disulfide (GSSG) is readily produced in cells in response to exogenous oxidants, supporting the concept that GSH is acting as a reductant in these situations [21, 57]

While many compounds can force the growth of new blood vessels (angiogenesis), they often do so in a disorganized way that can lead to leaky vessels or unwanted tissue growth