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But the "magnitude of the effects" was unexpectedly good compared to the three little-used FDA-approved medications for alcohol use disorder

Bradnam LV, Graetz LJ, McDonnell MN, Ridding MC

Low urinary pH predisposes for uric acid precipitation since the pKa of uric acid is 5.7, therefore the solubility of uric acid decreases with low pH, and thus increasing the risk of kidney stones ( Hypercalciuria has also been documented following keto-induction, with some studies documenting a 60% increase in excreted calcium, which could increase the risk of precipitation and developing kidney stones (73)

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