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Jump to: Who should never take weight-loss injections | Conditions that need extra caution | Medications that interact | Pregnancy, breastfeeding and age | If you are scheduled for surgery | When to stop and seek help | Questions to ask your GP | Frequently asked questions | Take home message You shouldnt take weight-loss injections like Wegovy (semaglutide) or Mounjaro (tirzepatide) if you have a personal or family history of medullary thyroid cancer, multiple endocrine neoplasia type 2 (MEN-2), type 1 diabetes, or have had a serious allergic reaction to a GLP-1 medication

Second, the doses are small because the target is a high-affinity intracellular enzyme, not a receptor that needs saturating with milligrams of drug

STEP-8: semaglutide 2.4 mg vs liraglutide 3.0 mg for weight management

Is 5-methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects