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Penicillamine, a copper chelator used in Wilson disease, requires dose adjustment in hepatic impairment precisely because liver function determines the rate at which mobilized copper can be processed and excreted [10]

Zhang, Shunjie

A significant portion of Americans have embraced freedom of therapeutic choice as a constitutional value for most of the countrys history, Lewis Grossman, a medical historian, writes in his book Choose Your Medicine. Benjamin Rush, a Founding Father and a physician, criticized the medical establishment for being closed-minded about treatments recommended by non-physicians

Less potent opioids are also used as cough suppressants and to treat diarrhea