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In contrast, in non-glucose starved cells, with the presence of 10 mM glucose in all perfusion buffers, no NADP oxidation was observed, even with continuous perfusion of buffer containing 20 M H 2 O 2

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Importantly, in vitro and in vivo , both the blocking of ATG5- and RAB7A-dependent lipid degradation and the enhancement of TPD52-dependent lipid storage prevents RSL3-induced lipid peroxidation and subsequent ferroptosis ( In addition, ferroptosis is also associated with a number of autophagy-related pathways

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