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This is particularly relevant for lean individuals or when using sites like the upper arm

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Activation of CaMK1 promotes synaptogenesis via phosphorylation of p21-activated kinase interacting exchange factor (PIX), which co-localises with the scaffolding proteins, G-protein-coupled receptor kinase-interacting protein-1 (GIT1) and Shank2, in the postsynaptic density of dendritic spines as part of a multiprotein complex that regulates actin dynamics [94, 99]