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Based on available research: Rapid systemic distribution following intraperitoneal injection in mouse models Detected in multiple tissues including skeletal muscle, liver, heart, and brain Crosses cellular membranes through mechanisms not fully elucidated Nuclear accumulation occurs within 30 minutes of metabolic stress Distribution studies suggest preferential accumulation in metabolically active tissues, particularly skeletal muscle where therapeutic effects are most pronounced

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have uterine fibroids and more than 15 million will experience symptoms or health concerns