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Alpha Lipoic Acid - anti-oxidant that boosts glutathione levels in cells

Acknowledgements This study was supported by Liaoning Plan Project of Science and Technology (Grant No

The reality is more layered

We previously demonstrated that melanocytes obtained from normally pigmented vitiligo skin show cellular and molecular alterations characterized by constitutive activation of antioxidant enzymes 1 and defects in mitochondrial metabolism reflected in altered expression and activity of complex I, increased generation of reactive oxygen species (ROS), low ATP production, and modified expression of some glycolytic enzymes 2