All in all, I do believe they represent significant positive steps in the way we treat cholesterol, and the way we will assess patients cardiovascular risk, said the Mayo Clinics Dr
Unlike subcutaneous fat, visceral fat is metabolically active and has been linked to several cardiometabolic changes, including: Insulin resistance Elevated inflammation Changes in blood sugar Increased cholesterol and triglycerides Over time, these changes can raise your risk of metabolic syndrome and cardiovascular disease
Statins inhibit hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, a key enzyme in cholesterol synthesis in hepatocytes, resulting in increased LDL receptor activity on these cells and increased clearance of lipoproteins containing apolipoprotein B-100, i.e., LDL and VLDL remnants (including intermediate density lipoprotein IDL) [35, 50]
Li J, Cao F, Yin H-l, Huang Z-j, Lin Z-t, Mao N, et al