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371 In osteoblasts, the administration of GLP-1 and GIP incretins suppressed the excessive expression of the pro-degradative enzymes MMP-3 and MMP-13 induced by IL-1 stimulation

Side Effects and Safety Considerations The most common side effects in trials were gastrointestinal including nausea, vomiting, and diarrhoea and were dose-dependent

17,499,500,501,502,503 Insulin resistance, a common occurrence in NASH patients, is a key driver of the diseases progression

Retatrutide is synthesized via solid-phase peptide synthesis and undergoes multi-stage purification to ensure high-purity analytical standards suitable for controlled research environments