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GLP-1 receptors are also expressed in the colon, where activation may improve the gut microbiome and reduce inflammation
Based on its unique metabolic regulation, inflammation inhibition, and appetite and gastrointestinal function regulation, Cagrlintide has shown significant potential for auxiliary regulation of gastrointestinal dysfunction, potential intervention in other digestive system diseases, and auxiliary improvement of recovery status in myocardial infarction patients
Although some studies suggest gastroparesis is more common in type 2 diabetes, the USA-funded National Institutes of Health Gastroparesis Clinical Research Consortium reported a comparable prevalence, especially in longstanding and poorly controlled diabetes
A Dual-Incretin Agonist Tirzepatide is called a dual-incretin agonist because it works on both GIP and GLP-1 receptors
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