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Decreases pigment

Data were corrected to baseline and vehicle treated samples

This reflects current thinking: using medications designed to work together (both GLP-1 pathways or combined GLP-1/GIP action) is safer than layering unrelated mechanisms

The robust presence of innate immune elements at the leading edges led some to conclude that in these chronic active MS lesions, there is a switch with the innate rather than the adaptive immune system taking over to propagate the pathology (Weiner, 2008)