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Between days 3 and 14, approximately 60-70% of users report some degree of noticeable appetite change

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285 , R470R478 (2003)

This includes people taking insulin or sulfonylureas, patients with diabetes, patients on blood pressure medications, patients with kidney disease or dehydration risk, patients with a gallbladder history, patients with significant reflux or gastroparesis symptoms, patients with eating disorder history, and patients who have difficulty meeting protein or fluid needs