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Moreover, SELENOM deletion inhibits the expression of FAO-related genes ( Ppara , Cpt1 , Cdh15 , Acox1 and Acadm ), and increases the expression of lipogenic genes ( Gpam , Plin1 , Scd1 , Lipe , Fasn , Acly, and Pparg ) ( NF-kB and Nrf 2 signaling), the Wnt signaling pathway, protein synthesis pathway ( 2 O 2 produced by thyroid cells during thyroid hormone synthesis, which can lead to thyroid cell necrosis and increased macrophage invasion in severe nutritional Se deficiency ( 6 Antioxidant mechanism of different Se forms in fish In the intensive aquaculture system, cultured fish mainly obtain the selenium from the feed
Neuroprotection Early studies suggest it may aid in protecting the brain and nerves after injury
Because B12 is primarily found in animal products (meat, fish, dairy, eggs), people following vegetarian or vegan diets may be at higher risk of deficiency
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