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In sym33-3 nodules, GSH levels were comparable to those of wild-type, while the hGSH content was higher, leading to a decrease in the GSH:hGSH ratio
This structure of the IGF1RIGF complex likely represents an intermedia state during IGF1R activation, however, as the two FnIII-3 domains (and presumably the kinase domains connected to them) remain separated by a long distance
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