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These include severe abdominal pain, persistent vomiting with inability to tolerate fluids, visual changes (especially for people with diabetes and existing retinopathy), signs of allergic reaction (rash, difficulty breathing, facial swelling), right upper quadrant pain with fever or jaundice (possible gallbladder disease), or symptoms of thyroid tumors (neck mass, hoarseness, difficulty swallowing)

Heliyon (2021) 7(5):e07064

They are used as biomarkers for a variety of diseases

They also should never be grouped with peptides used in bodybuilding or peptides researched for weight loss, as their mechanisms are entirely brain-centric