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That study enrolled 3,417 adults with obesity or overweight and without type 2 diabetes, and showed a mean weight loss of 22.7% at 68 weeks in patients who remained on treatment

[DOI] [PMC free article] [PubMed] [Google Scholar] 35.Loomba R., Hartman M.L., Lawitz E.J., Vuppalanchi R., Boursier J., Bugianesi E., Yoneda M., Behling C., Cummings O.W., Tang Y., et al

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No single or dual-agonist compound can replicate the combined effects on appetite regulation, insulin secretion, lipolysis, and thermogenesis that retatrutide produces in research settings