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Here, we establish membrane Paramagnetic Relaxation Enhancement (mPRE) Nuclear Magnetic Resonance (NMR), combined with nanodiscs as membrane mimics and optimized acquisition strategies, as an accessible solution for extracting membraneprotein distance constraints even for weakly bound systems

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Ikumi Tamai, Kanazawa University, Japan Updates Copyright 2020 Console, Scalise, Mazza, Pochini, Galluccio, Giangregorio, Tonazzi and Indiveri

LONG R3IGF-I as a more potent alternative to insulin in serum-free culture of HEK293 cells