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The treatment, in this case, usually follows by means of having daily injections for a week or so, then injections every few days for a month, after which maintenance doses are usually given every one to two months for life

Comment: A few commenters recommended CMS keep the requirement to encode the estimated allowed amount in the MRF instead of replacing it with the median allowed amount and adding the 10th and 90th percentile allowed amounts, indicating they believe that given the volume and complexity of the MRFs, the average would provide a more accurate estimate of what a hospital has historically received for that item or service

Holzenberger M, Dupont J, Ducos B, Leneuve P, Glon A, Even PC, Cervera P, Le Bouc Y (2003 Jan 9) IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

Biochemistry 38, 1055910566