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The absence of an ASP reporting requirement and inappropriate or no reporting of ASP could result in payment for a separately payable diagnostic radiopharmaceutical based on WAC or AWP indefinitely, a result which we believe would be inappropriate, as these pricing metrics do not capture all of the pricing discounts that may be reflected in the ASP
It also affects the parietal cells in stomach (parietal cells produce gastric acid to aid digestion of food) through the production of antiparietal cells antibodies results in chronic failure of gastric acid production
Cagrilintide is also being studied in combination with another medication (in a treatment known as CagriSema)
The high proline content (4 of 15 residues, including a triple Pro-Pro-Pro stretch at positions 3 to 5) gives BPC-157 unusually good resistance to gastric and intestinal proteases, which is why some published animal work uses oral administration
